Tetrahydrocannabinol (THC) belongs to a class of organic chemicals called phytocannabinoids. Discovered in the Cannabis sativa species, THC is commonly known for its psychedelic negative effects. When consumed (smoked, vaporized or eaten), THC mostly binds to the CB1 receptors in the tonsil, cerebellum and hippocampus.

Summary

Ranges of Cannabis sativa rich in THC (cannabis) are generally used for recreational functions. Marijuana is considered to be the most commonly used illegal drug in the world.

• THC can be produced synthetically

• Potential short-term disabilities in memory, coordination

• Potential increased cravings, frequently called “food yearnings”

• Responsible for the alteration of the mental state (effects).

• Strong affinity with CB1 receptors connected to the endocannabinoid system.

• Isolated for the first time in 1964.

• In regulated doses, connected to a possible treatment for numerous medical pathologies.

What research study states.

Due to the category of THC in Table I, research study on its healing applications is restricted. Research studies might be carried out offered that an administrative authorization letter is received first. Below is a choice of preclinical studies analyzing the effects of THC on nausea, numerous sclerosis and pain relief.

Dronabinol, an artificial THC drug, is approved by the United States Food and Drug Administration (FDA) for the treatment of chemo-induced nausea and throwing up (NVCI). A systematic study carried out in 2001 exposed that “cannabinoids have been used efficiently in the treatment of NVCIs since 1985”.

• Research 2.

A systematic evaluation in 2018 of “Cannabinoids for the treatment of numerous sclerosis signs” discovered that there is “evidence showing the advantages of treating spasticity and neuropathic pain in numerous sclerosis”. Researchers have explained that cannabis use carries a danger of undesirable negative effects.

• Research 3.

The Journal of Pain and Symptom Management published a study on the effect of THC extract: CBD and THC extract in clients with “intractable cancer pain”. The clients were randomized and the results compared with those of a placebo group. In general, the group of THC: CBD extracts discovered a substantial reduction in pain measurement (30%).

• Research 4.

Legal status.

In 1961, cannabis (due to its active constituent THC) was categorized as a narcotic in Table I. At the time, it was thought that there was “no medical use presently accepted which there was high capacity for abuse “.

The presence of THC in CBD oils and other cannabinoids is considered legal as long as the concentrations are listed below 0.2/ 0.3% (depending on the country).

A growing number of countries and states in the United States are beginning to alter their laws in favor of THC. In October 2018, Canada legislated cannabis for recreational and medical functions.

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